Resveratrol is a substance contained in grapes, peanuts as well as other fruits and plants. So, humans have ingested resveratrol since probably the beginning of time. But resveratrol supplements are relatively new and the amount of resveratrol, or trans resveratrol, ingested from supplements is much greater than would be ingested from eating grapes or peanuts or drinking red wine.
Resveratrol is being investigated all over the world for its potential positive side effects, but there are also some potential negative side effects, which are known.
The Most Common Resveratrol Side Effect
The most common minor side effect from taking resveratrol supplements is from a substance called Emodin and side effects associated with emodin can be easily avoided. Emodin is a laxative and it is commonly found in low-quality resveratrol supplements.
Resveratrol supplements that contain low-purity resveratrol contain high amounts of Emodin, while resveratrol products that contain high-purity resveratrol contains insignificant amounts of emodin. For more information on this, click here for our page on resveratrol warnings.
The common side effects from emodin can be diarrhea, excess gas and other annoying gastro-intestinal problems but these are easily avoidable. So, if you want to avoid this common side effect simply be sure that you are using a resveratrol supplement made with high-purity trans-resveratrol such as Perfect ResGrape.
Remember, Emodin is an impurity common in low-quality, low-purity resveratrol supplements. If a supplement contains anything less than 99% pure trans-resveratrol, that is indicative of a low quality resveratrol supplement with potentially problematic levels of emodin.
Other Potential Resveratrol Side Effects
- Joint pain, Tendinitis
- Stomach pain and diarrhea
- Discolored urine
- Insomnia, dizziness or jitters
This list is certainly not complete or scientific and is merely what some users of some resveratrol supplements have reported from various manufacturers. And it is not known if these potential side effects are from the resveratrol or from some other ingredient in the supplement.
Are there Long Term Resveratrol Side Effects?
As Web MD states, the long term studies on resveratrol side effects don’t exist so its impossible to say what the implications are, positive or negative, for the long term.
Here is what Web MD had to say about the potential positive side effects of resveratrol:
“These compounds are thought to have antioxidant properties, protecting the body against the kind of damage linked to increased risk for conditions such as cancer and heart disease. Resveratrol is found in the skin of red grapes, but other sources include peanuts and berries.”
And here is what Web MD had to say about potential negative resveratrol side effects:
“Because there have been very few studies conducted on resveratrol in humans, doctors still can’t confirm any benefits, and they don’t know what effects these supplements might have on people over the long term. So far, studies have not discovered any severe side effects, even when resveratrol is taken in large doses. However, resveratrol supplements might interact with blood thinners such as warfarin (Coumadin), and nonsteroidal anti-inflammatory medications such as aspirin and ibuprofen, increasing the risk for bleeding.
Like other supplements, resveratrol isn’t regulated by the FDA, so it’s difficult for consumers to know exactly what they’re getting when they buy a bottle, or whether the product is actually effective. There also isn’t any specific dosage recommendation, and dosages can vary from supplement to supplement.
The dosages in most resveratrol supplements are typically far lower than the amounts that have been shown beneficial in research studies. Most supplements contain 250 to 500 milligrams of resveratrol. To get the equivalent dose used in some animal studies, people would have to consume 2 grams of resveratrol (2,000 milligrams) or more a day.
The bottom line: Until more high-quality research is available, experts say they can’t recommend resveratrol supplements for antiaging or disease prevention.”
Also, don’t forget to read our page on resveratrol warnings.
Last but not Least…
…Consult With Your Doctor
Remember, you should consult with your doctor before starting any supplementation program. We are not giving any specific medical advice on this website, just general information. It is possible there can be interactions with your medications, so you want to check with your Doctor. In particular, anyone using a blood thinner should not use Resveratrol until it has been discussed with your doctor.